Copas from Milis sehat post by Gendi
Mau share saja mengenai perkembangan ilmu pengetahuan didalam mendiagnosa
TBC. Desember 2010 kemaren WHO sudah meresmikan untuk menggunakan tes
terbaru didalam mendiagnosa TBC, namanya *fully automated NAAT (nucleic acid
Metode tes terbaru ini melibatkan teknologi DNA dan akan menggantikan metode
tes TBC yg selama ini menggunakan sampel dahak. Metode ini hanya memerlukan
waktu 100 menit untuk mendapatkan hasilnya, yg bisa langsung mengetahui drug
resistant TB, dimana kalau cara lama yg menggunakan dahak perlu waktu hingga
Untuk lengkapnya silahkan baca artikel dibawah ini.
Gendi J – Father of 2
WHO endorses new rapid tuberculosis test A major milestone for global TB
diagnosis and care
*8 December 2010 | London | Geneva -* Today, WHO endorsed a new and novel
rapid test for tuberculosis (TB), especially relevant in countries most
affected by the disease. The test could revolutionize TB care and control by
providing an accurate diagnosis for many patients in about 100 minutes,
compared to current tests that can take up to three months to have results.
A major milestone
“This new test represents a major milestone for global TB diagnosis and
care. It also represents new hope for the millions of people who are at the
highest risk of TB and drug-resistant disease.” said Dr Mario Raviglione,
Director of WHO’s Stop TB Department. “We have the scientific evidence, we
have defined the policy, and now we aim to support implementation for impact
WHO’s endorsement of the rapid test, which is a fully automated NAAT
(nucleic acid amplification test) follows 18 months of rigorous assessment
of its field effectiveness in the early diagnosis of TB, as well as
multidrug-resistant TB (MDR-TB) and TB complicated by HIV infection, which
are more difficult to diagnose.
Increase in diagnosis
Evidence to date indicates that implementation of this test could result in
a three-fold increase in the diagnosis of patients with drug-resistant TB
and a doubling in the number of HIV-associated TB cases diagnosed in areas
with high rates of TB and HIV.
Many countries still rely principally on sputum smear microscopy, a
diagnostic method that was developed over a century ago. But this new ‘while
you wait’ test incorporates modern DNA technology that can be used outside
of conventional laboratories. It also benefits from being fully automated
and therefore easy and safe to use.
WHO is now calling for the fully automated NAAT to be rolled out under
clearly defined conditions and as part of national plans for TB and MDR-TB
care and control. Policy and operational guidance are also being issued
based on findings from a series of expert reviews and a global consultation
held last week in Geneva. The consultation was attended by more than a
hundred representatives from national programmes, development aid agencies
and international partners.
Affordability has been a key concern in the assessment process. Co-developer
FIND (the Foundation for Innovative and New Diagnostics) is announcing today
it has negotiated with the manufacturer, Cepheid, a 75% reduction in the
price for countries most affected by TB, compared to the current market
price. Preferential pricing will be granted to 116 low- and middle- income
countries where TB is endemic, with additional reduction in price once there
is significant volume of demand.
“There has been a strong commitment to remove any obstacles, including
financial barriers, that could prevent the successful roll-out of this new
technology,” said Dr Giorgio Roscigno, FIND’s Chief Executive Officer. “For
the first time in TB control, we are enabling access to state-of-the-art
technology simultaneously in low, middle and high income countries. The
technology also allows testing of other diseases, which should further
WHO is also releasing recommendations and guidance for countries to
incorporate this test in their programs. This includes testing protocols (or
algorithms) to optimize the use and benefits of the new technology in those
persons where it is needed most.
Though there have been major improvements in TB care and control,
tuberculosis killed an estimated 1.7 million people in 2009 and 9.4 million
people developed active TB last year.
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